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doi: 10.1186/1999-3110-55-7 52 FujikawaT.IshiharaH.LeachJ

6-Paradol increased tyrosine hydroxylase immunoreactivity and rescued dopaminergic neurons in the nigrostriatal pathway

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Residues in this domain can be oxidized by heme, allowing the protein RANBP2-type and C3HC4-type zinc finger containing 1 [RBCK1, also known as heme-oxidized IRP2 ubiquitin ligase (HOIL-1)] to mark it for degradation in response to heme availability (Wallander et al., 2008)

doi: 10.1371/journal.pone.0173911 27 Bravo-FerrerI.CuarteroM