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You can have the most brilliant hypothesis and a perfectly designed experiment, but if your reagents are compromised, the entire endeavor is built on a faulty foundation

For chronic alcohol users, vitamin B deficiency is common, and replenishing these vitamins is vital to support recovery and normal bodily functions

For SH-SY5Y/MYCN, the culture media was supplemented with 7.5 g/mL Blasticidin (Bio-Sciences) and 200 g/mL Geneticin (G418) (Thermo Scientific) for selection of the plasmid

That modification makes them highly toxic to liver cells

This was also confirmed in an experiment performed on male LIO rats, where tumor incidence depending on Epitalon administration and light exposure was investigated