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To test this hypothesis further, we added the cell-permeable GSSG in CD8 + T cell cultures

Few current clinical efforts are firmly based on sound preclinical rationale and investigate NCs as adjuncts to standard therapies rather than as active treatments per se

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The rash then becomes progressively more exudative, extends beyond skin folds, and finally causes cutaneous necrosis and ulceration

Both factors clear as the inflammatory response resolves, which is why the swelling typically improves within 24 hours