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Description

Special warnings and precautions for use: It is advisable to confirm the diagnosis of Vitamin B12 deficiency before giving hydroxocobalamin

PMID: 30266534 16

It's a frustrating, expensive, and entirely avoidable mistake

Common clinical drivers include: Vitamin B12 deficiency Folate deficiency Chronic liver disease Alcohol use disorder Medications (e.g., methotrexate) Bone marrow disorders Chronic inflammatory disease Hypothyroidism Key ICD-10 principle: Cell size is a laboratory observation