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Agati et al., 2011

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The anti-apoptotic subgroup encompasses BCL-2, BCL-XL, BCL-W, MCL-1, and A1/BFL-1, with BCL-2, BCL-XL, and BCL-W exhibiting remarkable stability and prolonged half-lives, in contrast to the rapid proteasomal degradation of MCL-1 and A1/BFL-1 through ubiquitination [41, 42]

in an orthotopic brain-tumor model, intrathecal administration further increased tumor uptake to 18.10 0.87%ID/g, with a tumor-to-brain ratio of 14.23 at 24 hsignificantly higher than blockade and isotype-control groups (p 100 days, and complete remissions were achieved in subcutaneous models [69, 70]

Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice