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Description

Elife 12 , e74915 (2023)

The ubiquitously expressed pyruvate dehydrogenase (PDH) carries pyruvate, via pyruvate dehydrogenation and formation of acetyl Coenzyme A, into the TCA cycle in both neurons and astrocytes, but no new TCA cycle intermediate is generated by the action of this enzyme alone

Conventionally, antibiotics are classified as cell wall inhibitors, protein synthesis inhibitors, nucleic acid synthesis inhibitors, antimetabolites, and cytoplasmic membrane inhibitors (Pancu et al., 2021