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Therefore, rational combination approaches that concurrently target MDSCs and the complex immunosuppressive network in the TME, together with biomarker-guided patient selection to enable personalized therapies, are critical for clinical success (7)

Berger MM

Acknowledgements AD and JCZ were supported by funds by the National Heart, Lung, and Blood Institute (NHLBI) (R21HL150032, R01HL146442, R01HL149714, R01HL148151)