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Allergy, Asthma & Clinical Immunology , 10 (1), p.58

Effect of L-methionine supplementation on plasma homocysteine and other free amino acids: a placebo-controlled double-blind cross-over study

In addition, chemical grafting to the 3 or 5 end can alter the tertiary structure of the aptamer which might be necessary for target binding

Because vitamin C helps keep the glutathione pool in its active form, your blood's overall antioxidant protection capacity may improve, rather than just the level of one nutrient in isolation