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In several studies, supplementation with carnitine was shown to improve constipation challenges

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Crucially, the selective deletion of mutant SOD1 specifically from astrocytes was shown to slow disease progression and extend the lifespan of these models, confirming the critical pathogenic role of astrocytes in ALS [314,323]

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For three of the six patients, we also co-treated slice cultures with RSL3 and Ferrostatin-1, ferroptosis inhibitor which we would expect to reverse the effects of the GPX4 inhibitor

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To overcome this limitation, dual-responsive ASP nanocarriers, sensitive to both pH and redox conditions, were developed to deliver ginsenoside Rh2 selectively to inflamed colonic sites

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Bio-stimulants have emerged as alternatives to chemical inputs, and promising approach to enhance crop growth, yield and, quality with less environmental damage 10

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