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There is no cloned DSIP receptor, no established binding site, and no accepted signal transduction pathway

doi: 10.1210/jc.2006-1375, PMID: [DOI] [PubMed] [Google Scholar] 3.Ognjenovic M, Ambrosini GL, Malacova E, Doherty DA, Oddy WH, Handelsman DJ, et al

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By enhancing GH signaling, tesamorelin may indirectly improve: Sleep depth Sleep recovery Morning energy Patients frequently report improved sleep quality during therapy, although this is not its primary indication