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Trial registration Similar content being viewed by others Introduction Metabolic syndrome (MetS) is defined as a cluster of cardiovascular risk factors (i.e., abdominal obesity, hyperinsulinaemia, atherogenic dyslipidemia, hypertension, hypercogauability) that increase the risk of developing co-existing coronary heart disease (CHD) and type 2 diabetes [1]

Trimethylaminuria is a rare condition that causes a buildup of the chemical trimethylamine in the body

(PubMed) Ershow AG, Skeaff SA, Merkel JM, Pehrsson PR

The high ROS environment lowers the activation threshold of mast cells, causing them to degranulate inappropriately and release a flood of inflammatory cytokines, including histamine, interleukins, and tumor necrosis factor-alpha (TNF-a)

In contrast, unsaturated fatty acids, particularly polyunsaturated fatty acids, have anti-inflammatory effects (Deja et al