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Notably, the phagocytosis of neutrophils was also shown to be affected in the results of this study

& Passalacqua, G

Possible pharmacological targets include the hypoxia-inducible factor (HIF) pathway, the Reperfusion Injury Salvage Kinase (RISK) 8 , the AMPK pathway 9 , the antioxidant transcription factor Nrf210 and autophagy, necrosis, and apoptosis pathways 11

In human neuroblastoma cells, microplastics have been shown to cause mitochondrial dysfunction, oxidative stress, and autophagy activation, leading to apoptosis with neurotoxic effects (26)

Despite advances that have reduced mortality and incidence, aSAH remains a significant public health concern due to its early onset, leading to prolonged periods of diminished quality of life for affected individuals