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Maslennikova, A.V

Polyphenols such as quercetin, kaempferol, and chlorogenic acid exhibit potent antioxidant and anti-inflammatory properties, which could protect skin cells from oxidative stress and delay aging

Specifically, treatment upregulates the molecular chaperone GRP78 to enhance protein-folding capacity and promote adaptation, while concurrently inhibiting the pro-apoptotic PERK/eIF2/CHOP axis and downstream activation of caspase-12 and caspase-3

Hallal N, Kharoubi O, Benyettou I et al (2016) In vivo amelioration of oxidative stress by Artemisia absinthium L

Therefore, BPC-157 PEN can be described as a research reagent of broad relevance in tissue biology analyses and preclinical models