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[] Another 8-week trial involving 52 benign prostatic hyperplasia (BPH) patients demonstrated that combined supplementation of lycopene and FruHis resulted in a more significant reduction in insulin-like growth factor 1 (IGF-1), total prostate-specific antigen (TPSA), symptom score, body mass index (BMI), and waist circumference (WC) compared with either supplement alone, with a notable effect observed specifically for IGF-1

No substantial protocol amendments affecting eligibility criteria, outcomes, or analyses were made after trial initiation

Currently, the manufacturer, Eli Lilly, has conducted TRIUMPH trials to check the efficacy of retatrutide in various health conditions, including obstructive sleep apnea, knee osteoarthritis, and type 2 diabetes

Table 1 Major microbes implicated in human AD

Tabin, G., Chen, M