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The role of steroids in the management of brain metastases: a systematic review and evidence-based clinical practice guideline

For clinical trial investigators, facilitating multidisciplinary collaboration among clinicians, supportive care providers, biochemists, and statisticians, improving the process of trial design and execution, as well as promptly and objectively reporting results, will contribute to generating higher-quality clinical evidence and benefiting a larger population affected by this chronic systemic disease

This leads to neuroinflammatory reactions and neuronal damage, triggering neuronal apoptosis cascade reactions (Tansey and Goldberg, 2010

Biochim Biophys Acta 2016;1864(3):268-279

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