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c , SK-N-SH, SH-SY5Y, HaCaT, and THP1 cells were stimulated with IFN (25 ng/mL) for 6 h, and total RNA was isolated for analysis of MXA transcripts by RT-qPCR (n = 3 biological replicates)

This study describes gp130SRCYAP signalling, which is independent of STAT3 activation, in regeneration and inflammation in the intestine and in the liver

Due to the high reactivity of Prx and Gpx (and abundance in the case of Prx), direct oxidation of GSH and other important redox-regulated proteins (like GAPDH or protein tyrosine phosphatase) are prevented up till the concentration of H 2 O 2 reaches tens of M -s, and hence, the redox signal that involves H 2 O 2 is most likely transmitted via Prx and/or Gpx

Romanov, V