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Junctophilin-2 (JPH2) anchors L-type Ca 2+ channels (LTCCs) and RyR2 in close proximity, facilitating the efficient activation of RyR2 by Ca 2+ ions entering the cardiomyocyte through LTCCs [Figure 1] [35]

Secretion, degradation, and elimination of glucagon-like peptide 1 and gastric inhibitory polypeptide in patients with chronic renal insufficiency and healthy control subjects

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