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Additional specific drugs and compounds of interest from which the drug moiety may be derived include, but are not limited to: Central nervous system depressants: general anesthetics (barbiturates, benzodiazepines, steroids, cyclohexanone derivatives, and miscellaneous agents), sedative-hypnotics (benzodiazepines, barbiturates, piperidinediones and triones, quinazoline derivatives, carbamates, aldehydes and derivatives, amides, acyclic ureides, benzazepines and related drugs, phenothiazines, etc.), central voluntary muscle tone modifying drugs (anticonvulsants, such as hydantoins, barbiturates, oxazolidinediones, succinimides, acylureides, glutarimides, benzodiazepines, secondary and tertiary alcohols, dibenzazepine derivatives, valproic acid and derivatives, GABA analogs, etc.), analgesics (morphine and derivatives, oripavine derivatives, morphinan derivatives, phenylpiperidines, 2,6-methane-3-benzazocaine derivatives, diphenylpropylamines and isosteres, salicylates, p-aminophenol derivatives, 5- pyrazolone derivatives, arylacetic acid derivatives, fenamates and isosteres, naltrexone, methylnaltrexone, etc.) and antiemetics (anticholinergics, antihistamines, antidopaminergics, etc.), analgesic agents as disclosed in U

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Elevated plasma levels of C4a serve as a surrogate biomarker for uncontrolled complement activation, correlating with symptom exacerbation, endothelial inflammation, and tissue-level hypoperfusion

It can help strengthen food security (Malik et al., 2023)

K., Burdette, S