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Inducers of the endothelial cell barrier identified through chemogenomic screening in genome-edited hPSC-endothelial cells

doi: 10.11002/fsp.2024.31.2.287 287 LabharAAhidarNEl-MernissiYBenamariOAit AllaKJahjahSet al

12 And because EPA and DHA are precursors for several metabolites that are potent lipid mediators, studies have considered them to prevent or treat many diseases, and their interactions with drugs like methotrexate, omega-3, and vitamin C have shown potential benefits

Specifically, since the early stages of the disease, AD brains are characterized by the presence of reactive microglia and astrocytes, which at the beginning release anti-inflammatory factors in the microenvironment, and later neurotoxic pro-inflammatory mediators, thereby exacerbating neurodegeneration

[DOI] [PubMed] [Google Scholar] Mayatepek E, Badiou S, Bellet H, Lehmann WD