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Additionally, in order to explore the mechanism of action being neuronal apoptosis, the research team assessed levels of neuroinflammation and glial activation by detecting levels of IL-1-beta, IL-10, and TNF-alpha in the brain

Acute incubation of glucose (20 mM) did not change NADPH levels in cytosol or mitochondria of HAECs (Supplementary Fig

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The anti-IL-10 antibody, BT063, is currently undergoing a phase II trial (NCT02554019)