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Generally, a daily intake of 500 mg to 2,000 mg is recommended for those looking to enhance exercise performance or support weight loss

SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells

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In liver injury, CHAC1s promotion of GSHdegradation accelerates oxidative stress and liver cell death, while in atherosclerosis, it contributes to plaque instability by promoting apoptosis in lesional macrophages and smooth muscle cells (Xu et al., 2023

Supplementary material The Supplementary Material for this article can be found online at: References 1 AmaralL