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Since monotherapy with metformin, PPIs, or HRAs, has been demonstrated to significantly deplete vitamin B 12 independently, co-prescription of these medications might induce an additive effect

The management guidance on precision medicine for different patients is still lacking

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Accordingly, we previously demonstrated that the secretion of IGF-1 (both proIGF-1s and mature IGF-1) was significantly lower in the cell overexpressing IGF-1Eb or IGF-1Ec isoforms compared to IGF-1Ea-transfected cells 7

First-line treatments: monotherapy with sodium channel blockers This group of drugs includes carbamazepine and oxcarbazepine (Table 8)