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Physiologically, at the cellular level, Mg 2+ is involved in metabolic pathways acting as an enzyme cofactor, contributes to the regulation of membrane stability, regulates ion channels, and acts as an intracellular signal [200, 201]

In HD, mitochondrial abnormalities including impaired respiration, altered calcium handling, and increased oxidative stress have been consistently reported [183, 184]

Bhat MH, Fayaz M, Kumar A, Jain AK

doi: 10.1038/ng.694 42 LiXLWuCFWuGS

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