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However, at 144 hpf, thyroid tissue appeared enlarged in around 55% (170/312) of the nrf2a crispants compared with their adamtsl2 crispants and noninjected siblings (Fig S1IL)

CD is a unique model of autoimmunity in which, in contrast to most other autoimmune diseases, a close genetic association with HLA genes, a highly specific humoral autoimmune response against tissue transglutaminase, and, most importantly, the triggering environmental factor (gliadin), are all known (6)

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1,6 References Chen, L., Zhu, Y., Hu, Z., et al

Simultaneous blockade of Histamine H(3) receptors and inhibition of acetylcholine esterase alleviate autistic-like behaviors in BTBR T+ tf/J mouse model of autism