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The application of synthetic cannabinoids (e.g., WIN55,212-2) were able to reduce the microglial release of these factors and directly act on primary astrocyte cells from mice to reduce hemichannel activation, preventing astrocytic uncoupling and maintaining gap junctions (Froger et al., 2009

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Finally, BPC 157 is listed as a prohibited substance by the World Anti-Doping Agency (WADA), all NCAA, and all professional anti-doping sporting agencies