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doi: 10.1016/j.ejphar.2012.11.055

Activation of liver X receptor increases acetaminophen clearance and prevents its toxicity in mice

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Peptidylarginine deiminase 4 promotes age-related organ fibrosis

143,149,154 An imbalance in the gut microbiota can elevate uric acid concentrations, thereby exacerbating the chronic deposition of UA crystals in joints, characteristic of gout