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This peptide is commonly incorporated into copper peptide serums and peptide creams for topical application

Ipamorelin + GHK-Cu Stack: Safety and Monitoring Guide At a glance Ipamorelin class / selective GHRP (growth hormone releasing peptide), no cortisol or prolactin spike GHK-Cu class / copper-binding tripeptide, endogenous wound-repair signal Typical Ipamorelin dose / 200 to 300 mcg subcutaneous, 1 to 3x daily Typical GHK-Cu dose / 1 to 2 mg subcutaneous or topical per application Primary safety concern / IGF-1 elevation with Ipamorelin

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[PMC free article: PMC2630862] [PubMed: 18984660] 78

Six clinical trials involving 893 participants produced adverse event rates statistically indistinguishable from placebo