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460 Upon ROS-triggered release in cancer cells, ES and Cu synergistically amplify ROS, inducing cuproptosis and stimulating immune responses

Jun 7 2017;18(6)doi:10.3390/ijms18061221

The total cellular GSH concentration was assessed

At the same time, the study also found that Polyphyllin III treatment induced a protective upregulation of xcT, a negative regulator of ferroptosis

To verify our hypothesis, we performed sandwich ELISAs using a rabbit anti-PV1 pAb as the capture antibody, different mAbs as detection antibodies, and the international cIPV standard (NIBSC code: 12-104) as the reference