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The silencing efficiency of MDA-MB-231, MIA PaCa-2, and SW1990 reached a plateau only one day after transfection, and that of other cells also reached a plateau on Day 2 (Fig

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Patients were randomized 3:1 in a blinded manner to receive resmetirom 80 mg or matching placebo given orally once daily in the morning for the duration of the study (until the required number of Composite Clinical Outcome events are achieved)