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Description

Nat Microbiol 2:16268

Nat Rev Endocrinol 21(8):495509

That may show up as achy joints, skin breakouts, or headaches

In turn PDK1 phosphorylates Akt in T308 (46), however the maximal activation of Akt requires its additional phosphorylation on S473 located at the carboxyl-terminus site, mediated by mTORC2 (47)