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Further evidence from animal studies suggests DSIP influences blood pressure, heart rate, thermoregulation, and the lymphokine system, with some effects observed independently of sleep onset

Structural features of Cagri-bound active CTR complexes Previous structural analysis of CTR-Gs bound to rAmy revealed that the receptor complex was dynamic, adopting distinct states where the receptor was resolved into two major conformations, a bypass (55%, PDB: 7TYL) and CT-like (45%, PDB: 7TYI) conformation 15