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The overexpression of P-gp and BCRP correlates with an onset of resistance and suboptimal clinical outcomes in individuals with metastatic breast cancer, acute and chronic lymphocytic leukaemia, myeloma, and acute myelogenous leukaemia [44]

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Metabolite identification is achieved through spectral database matching (e.g., HMDB, METLIN), followed by statistical analysis (PCA, PLS-DA) and pathway enrichment (KEGG, MetaboAnalyst) to interpret biological significance (Kumar et al., 2020

Malnutrition During Pregnancy, a Transgenerational Problem: Transgenerational Inheritance and the Paternal Role One of the most emblematic examples of how maternal malnutrition can exert long-lasting and even transgenerational effects is the Dutch Hunger Winter