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The rationale for stacking GHK-Cu vs NAD+ together is additive rather than synergistic: GHK-Cu handles structural repair while NAD+ handles bioenergetics

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The squaramide, IT-066 displaced the binding of [ 3 H]tiotidine to cells transfected with the wild-type H 2 -receptor in a concentration-dependent manner (Figure 58) [185]