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High-dose levocarnitine can also antagonize the intracellular actions of thyroxine and triiodothyronine by limiting their nuclear uptake

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This variability could affect the reliability and comparability of the findings across different studies

L-Carnitine provides the fat loss benefits, whereas the Acetyl L-Carnitine provides those same benefits, with the added bonus of being processed, so that it penetrates the blood-brain barrier quicker, and therefore also provides mental health benefits

It has been suggested that VHT and VHE may be promoted by carnitine deficiency, either pre-existing or deficiency induced by VPA [134]