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[PubMed: 12949285] Drewnowski A, Yee DK, Kurth CL, Krahn DD

The chromatographic procedures involved the use of a C 18 column (100 2.1 mm, 1.7 m) with a binary mobile phase mixture of methanol and water (50:50, v/v) at a flow rate of 0.3 ml/minute in a total run time of 3.8 min

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Thus cigarette smoking produced nicotine dose-related effects on HPA hormones and subjective and cardiovascular measures

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