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This orchestrated modulation culminates in the induction of iron-dependent ferroptosis (Park and Chung, 2019)

Continuous, subcutaneous apomorphine infusion for Parkinson disease motor fluctuations: results from the phase 3, long-term, open-label United States InfusON study

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For instance, gabapentin and pregabalin which are known to inhibit calcium influx via the calcium channel 21 subunit, effectively reduce the hyperalgesia for mechanical and thermal stimuli in various type of neuropathic pain (McGivern, 2006)

PEG-lipid components are reported as the underlying reason for the side effects through mechanisms i and ii (Khalid and Frischmeyer-Guerrerio, 2023), while mechanism iii is mainly caused by mRNA-LNP itself when it is recognized as a self-antigen that can initiate autoimmune diseases