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In intrauterine adhesion models, semaglutide demonstrated anti-fibrotic properties, inhibiting epithelial-mesenchymal transition (the process by which epithelial cells transform into fibrotic, scar-like tissue)

This pathway thus represents a promising therapeutic target 15

Run together, they are described in research-use contexts as creating a more complete environment for soft-tissue repair than either compound alone, which is why athletes and recovery-focused researchers gravitate to this stack for tendinopathy, ligament strain, and post-surgical recovery rehabilitation models

doi: 10.1016/j.biopha.2023.114241 88 LiangDFengYZandkarimiFWangHZhangZKimJet al

Development of bioinspired functional chitosan/cellulose nanofiber 3d hydrogel constructs by 3d printing for application in the engineering of mechanically demanding tissues