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We conducted a literature search using PubMed to identify the risk of ophthalmic-specific drugs in patients with a self-reported sulfonamide allergy

Their results revealed that decreasing NNMT expression in primary hepatocytes led to a reduction in the expression of phosphoenolpyruvate carboxykinase 1 (Pck1) and glucose-6-phosphatase (G6pc), resulting in decreased glucose output

Marseglia, L., DAngelo, G., Manti, S., Reiter, R

Reduction in Radiation-Induced Immune System Suppression with Proton Therapy - An Overlooked Additional Benefit

It reveals that selective ubiquitin-proteasomal degradation of PHGDH may be a more viable therapeutic strategy compared to PHGDH enzyme inhibitors