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Also, 5-AAO (5a-dC) is a nucleoside analog of cytidine

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Consistently, in a CRPS model, the spinal cord showed increased populations of reactive astrocytes and microglia were observed in the spinal cord, along with elevated expression of the M1 marker CD86 and reduced Arg-1 expression, indicating a preferential M1 microglial polarization in NPP (122)