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748 Inhibition of this pathway using the PAR1 antagonist vorapaxar has been shown to reduce the burden of senescent cells, offering a potential therapeutic strategy

Specifically, the absence of PDK1 hinders PKC activation and prevents the formation of the CBM complex (81)

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Furthermore, elevated levels of inflammatory and oxidative stress markers, such as TGF- and VEGF, suggesting that inflammation plays a critical role in disease progression (319, 320)

Choice B: The bundle of His can be the origin for junctional tachycardias