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289,290 A controlled trial in 46 women with fibromyalgia found that eating a low-FODMAPs and anti-inflammatory (no gluten, dairy, added sugars, or ultra-processed foods) diet for one month, followed by two months of adherence to the anti-inflammatory practices, resulted in improved pain, symptom severity, sleep, fatigue, and quality of life scores compared with general healthy eating practices

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DSIP Mechanisms (What We Actually Know) Animal models show the following: Dose-dependent antinociceptive effects (pain reduction) Naloxone blockade, indicating opioid receptor involvement The effects on human subjects appear to be broader: Stress modulation Neurotransmitter regulation Possible circadian interaction The exact receptor targets remain undefined as of now, which means the optimal subcutaneous dose of DSIP has not been scientifically established

Laparoscopic management of large hiatus hernia: five-year cohort study and comparison of mesh-augmented versus standard crura repair

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