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Description

Chang et al., 2021

Exhaustion is the result of prolonged antigenic stimulation along with inflammatory signals

The structure of LEPR LEPR is encoded by the LEPR gene, which is 1165 aa in length and has a molecular weight of approximately 132,4 kDa type I transmembrane protein, composed of three parts: intracellular region, transmembrane region and extracellular region , and generates multiple isomers (such as long LEPR-b, short LEPR-a/c/d/f, soluble LEPR-e) through selective splicing