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Ferrell, M

Autophagy increases H 2 O 2 levels by promoting p53-mediated GSH depletion and inducing Bcl2 interacting protein 3 (BNIP3) upregulation, mitochondrial damage, and AIF translocation from the mitochondria to the nucleus, resulting in glioma cell death (Wang et al., 2020)

These suggest that LMP precedes PM disintegration in ferroptotic cells, but not in cells with STS-induced apoptosis

Danielle Blundell is a New Jersey-based lifestyle writer and editor who has written on topics ranging from home and health to beauty for a variety of publications, including Rachael Ray Every Day, Redbook, Family Circle , This Old House , Elle Decor , Esquire , Domino, and Apartment Therapy

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