For performance year 2025 and subsequent performance years, we proposed to require Shared Savings Program ACOs to report the APP Plus quality measure set as proposed in section III.G.4.b.(2)(a) of the CY 2025 PFS proposed rule (89 FR 61854 through 61855)
If your protocol requires doses under 3mg, consider reconstituting with a larger solvent volume to increase injection volume and improve accuracy
The following provides additional information about the CPT and HCPCS codes that we proposed to add to the definition of primary care services used for purposes of beneficiary assignment: Safety Planning Interventions (SPI) (HCPCS code GSPI1 (Safety planning interventions, including assisting the patient in the identification of the following personalized elements of a safety plan: recognizing warning signs of an impending suicidal crisis
Heavier individuals may require higher doses to achieve equivalent NNMT inhibition due to larger adipose tissue mass and potentially higher baseline NNMT activity
Visceral fat exhibits higher metabolic activity, greater innervation, richer blood supply, and importantly, higher concentrations of beta-3 adrenergic receptors compared to most subcutaneous depots
