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Description

TTC5 has previously been shown to downregulate ATP synthase activity, which sensitizes cells to mitochondrial-dependent apoptosis via enhanced p53 activity (72)

In vitro cellular senescence models (such as senescence models of human fibroblasts, hepatocytes, and nerve cells) are common tools for studying aging mechanisms and interventional drugs

These medicines have well-characterised safety profiles and are prescribed within a structured clinical pathway that includes monitoring and follow-up