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Therapeutic inhibition of ferroptosis in neurodegenerative disease

11:eadr8243

When SAM-e loses a methyl group, it becomes SAH (s-adenosyl-homocysteine), which then is hydrolyzed to form homocysteine.[ref] This is called the methylation cycle or the methionine cycle

Although being rather contradictory, the existing data demonstrate that the metabolic effects of Zn in obesity may be associated with its interference with leptin production