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Among all of the flavonoids found in nature, quercetin (QU) stands out for its antioxidant and anti-cancer capabilities (Huang et al

& Satishchandran, A

Its depletion can increase the toxicity of arsenic in various cell types via mechanisms including increased oxidative stress and free active arsenic concentration, loss of arsenic-bound mercaptan, and reduction in the detoxification by GSHdependent methylation and the binding of arsenic to GSH

Current research emphasizes neutrophil activation, recruitment, and NETs production, which could inform therapeutic strategies targeting neutrophils for the prevention and treatment of CVDs