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We approached these issues by applying (1) affine registration for T1W MRI data and (2) rigid registration to the unbiased MNI152 template on the raw whole brain data and then (3) minimizing the between-cohort appearance difference using a dynamic histogram warping (DHW) algorithm (Cox et al., Supplementary Figure S4a

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KPV is a short peptide derived from alpha-MSH (melanocyte-stimulating hormone) sequences and is studied for anti-inflammatory signaling, including effects on cytokines (chemical messengers of inflammation) and gut inflammation models

Not all research chemical vendors adhere to these practices, which is why researchers should perform due diligence when selecting the right vendor Using peptides from questionable vendors may compromise the safety and effectiveness of the experiment