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Running exercise has been reported to reduce microglial activation and improve neuroinflammatory profiles in hippocampal models of stress-induced depression [338,339,340,341]

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Miyamoto K, Nakanishi H, Moriguchi S, Fukuyama N, Eto K, Wakamiya J, Murao K, Arimura K, Osame M (2001) Involvement of enhanced sensitivity of N-methyl-d-aspartate receptors in vulnerability of developing cortical neurons to methylmercury neurotoxicity

Metabolomic profiles and associated metadata for the three IBD cohorts were also obtained from published studies and are publicly available as follows: for BushmanFD_2020, data are available on GitHub ( for LloydPriceJ_2019, data are available in the Metabolomics Workbench database under Project ID PR000639