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doi:10.17245/jdapm.2018.18.6.333 Albrecht M, Levin M

Lancet Public Health 3: e419e428 Sena L, Li S, Jairaman A, Prakriya M, Ezponda T, Hildeman D, Wang CR, Schumacker P, Licht J, Perlman H et al (2013) Mitochondria are required for antigenspecific T cell activation through reactive oxygen species signaling

For example, Tongyang Huoxue decoction (TYHX) protects sinoatrial node cells (SNC) by stabilizing the stability of -tubulin and sirt1 through VDAC1 to inhibit mitochondrial stress and excessive SNC division

Quantifying endotoxin at the batch level allows a research team to reason about whether an observed cellular response reflects receptor pharmacology or a contaminant-driven artifact